Friday, July 10, 2015
Findings on Dementia
Results from 7 studies about what things boost risk of your brain failing you as you age. Two thing to remember. a) Your body has only one thing it can do when something is wrong (toxins, deficiencies, injuries, micro invaders)--anything wrong, it cranks up inflammation. If it gets cranked up and never allowed to shut down it causes damage. Where that damage shows up for you is individual, but the biggies in the category of diseases of civilization are the heart, metabolism, brain and malignant growths. Ultimately they all are part of a network (you). All the info below ties to the inflammation thermostat.
b) correlation does not equal cause but it's certainly suggestive. My own feeling is that is eliminating something correlated with dementia is likely to help and non toxic, I don't need to wait for the final proof.
1. People who were underweight in middle age were a third (34%) more likely to be diagnosed with dementia than those of a healthy weight, and this increased risk of dementia persisted even 15 years after the underweight was recorded.
2. This is the first study to show a dose response: linking more risk for developing dementia to higher use of anticholinergic medications. And it is also the first to suggest that dementia risk linked to anticholinergic medications may persist -- and may not be reversible even years after people stop taking these drugs.(doxepin (Sinequan), first-generation antihistamines like chlorpheniramine (Chlor-Trimeton), and antimuscarinics for bladder control like oxybutynin (Ditropan). and Benadryl.)
3. Vitamin D deficiency is associated with a substantially increased risk of dementia and Alzheimer's disease in older people, according to the most robust study of its kind ever conducted. "We expected to find an association between low Vitamin D levels and the risk of dementia and Alzheimer's disease, but the results were surprising -- we actually found that the association was twice as strong as we anticipated. and their new findings confirm that vitamin D levels above 50 nmol/L are most strongly associated with good brain health.
4. 35-year period has confirmed exercise significantly reduces the risk of dementia. The study identifies five healthy behaviors as having the best chance of leading a disease-free lifestyle: taking regular exercise, non-smoking, a low body weight, a healthy diet and a low alcohol intake. "What the research shows is that following a healthy lifestyle confers surprisingly large benefits to health -- healthy behaviors have a far more beneficial effect than any medical treatment or preventative procedure.
5. "The study demonstrates why it is so crucial for people with diabetes to work closely with health care providers on controlling their blood sugar," Chiu said. "Managing the disease can help prevent the onset of dementia later in life."
6. Depression and type 2 diabetes mellitus were each associated with an increased risk for dementia and that risk was even greater among individuals diagnosed with both depression and diabetes.
7. Diabetes is a risk factor for dementia. But now a study has found that higher blood sugar levels are associated with higher dementia risk, even among people who do not have diabetes. "While that is interesting and important, we have no data to suggest that people who make changes to lower their glucose improve their dementia risk. Those data would have to come from future studies with different study designs."